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The term “propofol infusion syndrome” (PRIS) first appeared in pediatric literature and was proposed by Bray who had reviewed 18 pediatric cases [5]  The clinical spectrum of PRIS consists of bradycardia, cardiovascular collapse, HAGMA, rhabdomyolysis, hepatomegaly, and lipemia [5] Propofol infusion syndrome (PRIS) is a rare and potentially fatal condition that was first reported in children in 1990  It is characterized by profound metabolic acidosis and bradycardia which may ultimately lead to cardiac arrest pmc ncbi nlm nih gov articles PMC4470532first10em com propofol-related-infusion-syndrome-prisAside from propofol dose, other risk factors for PRIS include critical illness, use of vasopressors and steroids, starvation or malnutrition, and subclinical mitochondrial disease Propofol-related infusion syndrome (PRIS) is a lethal condition characterized by multiple organ system failures  It can occur due to prolonged administration of propofol (an anesthetic) in mechanically intubated patients Mechanism of PRIS High doses of propofol (greater than 3mg kg h) lead to direct inhibition and uncoupling of mitochondrial electron transport chains, leading to greater reliance on anaerobic metabolism en wikipedia org wiki Propofol_infusion_syndromePropofol-related infusion syndrome (PRIS) is a lethal condition characterized by multiple organ system failures  It can occur due to prolonged administration of propofol (an anesthetic) in mechanically intubated patients cumming ucalgary ca     CPT%20Pearl%20Propofol%20Related%20Infusion%20Syndrom   litfl com propofol-related-infusion-syndromePropofol-related infusion syndrome (PRIS) is a rare but severe condition associated with the administration of propofol, an anesthetic commonly used for sedation in medical procedures  First identified in the 1990s, PRIS can be fatal if not recognized and treated promptly Propofol infusion syndrome (PRIS) is a rare propofol complication, leading to cardiac failure  It was first described in critically ill children and in adults with traumatic brain injury anesthesiologydfw com propofol-related-infusion-syndromeMechanism of PRIS High doses of propofol (greater than 3mg kg h) lead to direct inhibition and uncoupling of mitochondrial electron transport chains, leading to greater reliance on anaerobic metabolism pmc ncbi nlm nih gov articles PMC9671386May 13, 2021 · Propofol infusion syndrome (PRIS) is a rare and potentially fatal condition that was first reported in children in 1990  It is characterized by profound metabolic acidosis and bradycardia which may ultimately lead to cardiac arrest Propofol infusion syndrome (PRIS) is a multifactorial condition that, upon propofol administration, can interrupt critical cellular processes  This can lead to cellular damage that translates as multi-organ system failure that has the potential to be life-threatening Propofol-related Infusion Syndrome (PRIS) is a life-threatening condition characterised by acute refractory bradycardia progressing to asystole and one or more of:Propofol infusion syndrome (PRIS) is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug propofol Propofol infusion syndrome (PRIS) is a multifactorial condition that, upon propofol administration, can interrupt critical cellular processes  This can lead to cellular damage that translates as multi-organ system failure that has the potential to be life-threatening Apr 30, 2024 · Propofol-related infusion syndrome (PRIS) is a rare but severe condition associated with the administration of propofol, an anesthetic commonly used for sedation in medical procedures  First identified in the 1990s, PRIS can be fatal if not recognized and treated promptly pmc ncbi nlm nih gov articles PMC9794362pmc ncbi nlm nih gov articles PMC4410753Propofol infusion syndrome (PRIS) is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug propofol Feb 5, 2024 · Aside from propofol dose, other risk factors for PRIS include critical illness, use of vasopressors and steroids, starvation or malnutrition, and subclinical mitochondrial disease resusnation com propofol-infusion-syndromePropofol-related Infusion Syndrome (PRIS) is a life-threatening condition characterised by acute refractory bradycardia progressing to asystole and one or more of:The term “propofol infusion syndrome” (PRIS) first appeared in pediatric literature and was proposed by Bray who had reviewed 18 pediatric cases [5]  The clinical spectrum of PRIS consists of bradycardia, cardiovascular collapse, HAGMA, rhabdomyolysis, hepatomegaly, and lipemia [5] Propofol infusion syndrome (PRIS) is a rare propofol complication, leading to cardiac failure  It was first described in critically ill children and in adults with traumatic brain injury 

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