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morphine, codeine, fentanyl, methadone, tramadol, and other similar substances  Their regular non    Drug-resistant TB continues to pose a serious threat, with 150 000 new cases estimated in 2024  The Region has reduced TB incidence by 16% since 2015, slightly faster than the global average of 12%  But deaths are not falling fast enough, and the Region’s TB incidence rate of 201 per 100 000 people – remains well above the global average of    In the Anatomical Therapeutic Chemical (ATC) classification system, the active substances are divided into different groups according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties  Drugs are classified in groups at five different levels --- who int tools atc-ddd-toolkit atc-classificationThe use of psychoactive drugs without medical supervision is associated with significant health risks and can lead to the development of drug use disorders  Drug use disorders, particularly when untreated, 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