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Laboratories Network of the Council of Europe (17) Drug consumption can be expressed in cost, number of units, number of prescriptions or by the physical quantity of drugs However these variables can vary between regions and countries over time This limits comparisons of drug consumption at an international level To address this, a technical unit of measurement, the Defined Daily Dose (DDD) was created About WHO Drug Information WHO Drug Information is a quarterly journal providing an overview of topics relating to medicines development and regulation which is targeted to a wide audience of health professionals and policy makers Launched in 1987, WHO Drug Information communicates the latest international news and trends to regulatory agencies, academic and training institutions, researchers As a result of drug resistance, antibiotics and other antimicrobial medicines become inefective and infections become increasingly diicult or impossible to treat --- who int tools atc-ddd-toolkit atc-classificationFor drug-drug interactions the WHO-UMC system can be used by assessing the actor drug, which influences the kinetics or dynamics of the other drug (which has usually been taken over a longer period), in the medical context of the patient As a result of drug resistance, antibiotics and other antimicrobial medicines become inefective and infections become increasingly diicult or impossible to treat Good Manufacturing Practices (GMP, also referred to as 'cGMP' or 'current Good Manufacturing Practice') is the aspect of quality assurance that ensures that medicinal products are consistently produced and controlled to the quality standards appropriate to their intended use and as required by the product specification For drug-drug interactions the WHO-UMC system can be used by assessing the actor drug, which influences the kinetics or dynamics of the other drug (which has usually been taken over a longer period), in the medical context of the patient Note: For further guidance on validation of data-processing equipment, refer to documents published by the International Society for Pharmaceutical Engineering (13, 14), US Food and Drug Administration (15), European Commission (16) and the Offi cial Medicines Control Laboratories Network of the Council of Europe (17) --- who int docs default-source antimicrobial-resistance amr-factsheet pdf--- who int teams health-product-policy-and-standards gmp1 Introduction and background Manufacturers should ensure that the products that they manufacture are safe, efective and of the quality required for their intended use Systems should be in place to ensure that pharmaceutical products are produced according to validated processes and to defined procedures Manufacturing processes should be shown to be capable of consistently manufacturing --- who int tools atc-ddd-toolkit about-dddOur team provides authoritative guidance and standards on quality, safety and efficacy of health products and supports countries to formulate evidence-based policies and ensure good practice throughout the value chain Good Manufacturing Practices (GMP, also referred to as 'cGMP' or 'current Good Manufacturing Practice') is the aspect of quality assurance that ensures that medicinal products are consistently produced and controlled to the quality standards appropriate to their intended use and as required by the product specification About WHO Drug Information WHO Drug Information is a quarterly journal providing an overview of topics relating to medicines development and regulation which is targeted to a wide audience of health professionals and policy makers Launched in 1987, WHO Drug Information communicates the latest international news and trends to regulatory agencies, academic and training institutions, researchers Drug consumption can be expressed in cost, number of units, number of prescriptions or by the physical quantity of drugs However these variables can vary between regions and countries over time This limits comparisons of drug consumption at an international level To address this, a technical unit of measurement, the Defined Daily Dose (DDD) was created Our team provides authoritative guidance and standards on quality, safety and efficacy of health products and supports countries to formulate evidence-based policies and ensure good practice throughout the value chain Drug Utilization Research (DUR) uses the Anatomical Therapeutic Chemical (ATC) as the classification system and the Defined Daily Dose (DDD) as a unit of measure The ATC classification system groups the active medical substances according to the organ or system on which they act and according to their therapeutic, pharmacologic and chemical properties The DDD is a unit of measurement and is --- who int teams health-product-and-policy-standards innDrug Utilization Research (DUR) uses the Anatomical Therapeutic Chemical (ATC) as the classification system and the Defined Daily Dose (DDD) as a unit of measure The ATC classification system groups the active medical substances according to the organ or system on which they act and according to their therapeutic, pharmacologic and chemical properties The DDD is a unit of measurement and is --- who int docs default-source medicines whocausality-assessment pdf--- who int docs default-source medicines trs992-annex4 pdf--- who int tools atc-ddd-toolkit methodologyIn the Anatomical Therapeutic Chemical (ATC) classification system, the active
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